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Ageing

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Electrostatic surface of memapsin; key protease in the Alzheimer's disease
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Rheumatoid arthritis
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Alzheimer's amyloid plaque

Agriculture

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Protease inhibitors as new pesticides, insecticides, herbicides
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Protease research aids the development of new pesticides

Conception and Birth

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Proteases are very important in human development.
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Embryo

Death and Disease

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Proteases can be used to treat cancers such as Melanoma.
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Cystic fibrosis cell with bacteria
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Dengue Virus NS3 protease complexed with Bowman Birk inhibitor (yellow)
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Dustmites secrete proteases associated with asthma.
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Protease research is producing medicines to treat parasites such as hookworms.
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HIV-1 protease required for HIV replication
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Dipeptidyl peptidase IV important in Type II diabetes
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Renin inhibitors are anti-hypertensive.
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Leucine aminopeptidase in the gut of the parasitic Schistosoma mansoni
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Hookworm
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Blood fluke associated with schistosomiasis.

Life

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Complex Of Xiap-Bir2 And Caspase 3
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Membrane spanning Aspartic protease
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Tricorn protease
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Serpin - protease complex
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Comparison of active sites of Thrombin (left) and Factor Xa
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Structure of the serine protease Trypsin displaying its characteristic fold

Miscellaneous

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Diagramatic representation of the role of proteases.






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